One suggestion I have is to be sure to have a cooler with ice with you. I traveled with my 2 Italian Greyhounds long distance several times and they did awesome in their crates. However on one trip, we got stuck on an Interstate for over two hours due to an accident ahead of us. Had to turn the car off to avoid overheating and wasting gas. Fortunately I was prepared with ice. I take ziplock bags, fill them with ice, wrap in a towel and put in their crate. Helps cool them. Also take a washcloth that you can soak in cool water to rub their chests and feet. This is what my vet says to cool them off. I also would rub their heads and faces. Dogs can get heat stroke as well. One of them refused to drink on trips so I carried a medicine syringe (like you use for kids oral meds). I'd squirt some in his mouth so at least he was getting a little water. He thought it was more fun to chew it!. It's safest for them to travel in their crates, just make sure they are getting good ventilation from the a/c or heater in winter. If not crated, invest in a vest/harness that allows you to slide the seat belt through it and this will keep them in place, yet allow them to lay down or sit up and keep them from flying off the seat if you have to stop suddenly. I always bring their own beds and toys as well as food and water bowls. As far as hotels, check in advance even if it says pet friendly. When I moved for a job, I stayed in a Marriott Extended stay and they were awesome. They had a tag to hang on the door that said "Pet inside, do not enter" so the room cleaners could come back when we were out on our evening walks. I was always worried someone would open the door and they could escape. Give yourself plenty of time to travel because of the frequent stops. My IG Prince was really smart and funny. After the first roadside park stop, he realized if he started whining I would find a place to let them out to potty. Problem is, he didn't need to go, just wanted to snoop around on leash wherever it was we stopped. Took me a couple of stops to realize what the stinker was up to! Have a safe journey.