I was raised in a household with at least 2 dogs at a time, not including the ones that we would foster here and there and I have been pet sitting for 4 years; throughout my time doing so I have meet all types of dogs with a variety of personalities and temperaments. I have worked with great danes to chihuahuas, including (mostly) mutts of different sizes. I have had to deal with very old and sickly pets that required a lot of time and devotion, and I have dealt with very young puppies that required constant watch. Many of the dogs I pet-sit have separation anxiety and/or have a problem with new people, it is not an issue. I have no problem with cleaning up accidents and messes that occur. (I have also cared for cats, ferrets, rats, mini-pigs, various types of bird, reptilians, and tarantulas)